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pirA pirA pfeA pfeA fpvB fpvB PA2689 PA2689 PA2983 PA2983 fepB fepB PA0444 PA0444 fepD fepD PA2289 PA2289 tonB1 tonB1 phuR phuR
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
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Gene Fusion
Cooccurrence
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Experiments
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[Homology]
Score
pirAFerric enterobactin receptor PirA; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa). (742 aa)    
Predicted Functional Partners:
pfeA
Ferric enterobactin receptor, outer membrane protein PfeA precursor; Specific receptor for the siderophore ferric enterobactin.
  
 
0.915
fpvB
Second ferric pyoverdine receptor FpvB; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa).
  
  
 0.773
PA2689
Hypothetical protein; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences).
 
  
 0.743
PA2983
Probable tolQ-type transport protein; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene).
 
  
 0.723
fepB
Ferrienterobactin-binding periplasmic protein precursor FepB; Product name confidence: Class 2 (High similarity to functionally studied protein).
  
  
 0.718
PA0444
N-carbamoyl-beta-alanine amidohydrolase; Product name confidence: Class 2 (High similarity to functionally studied protein).
      
 0.699
fepD
Ferric enterobactin transport protein FepD; Product name confidence: Class 2 (High similarity to functionally studied protein); Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
  
  
 0.696
PA2289
Conserved hypothetical protein; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences).
  
  
 0.682
tonB1
TonB1; Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy-requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins (By similarity).
 
 
 0.673
phuR
Heme/hemoglobin uptake outer membrane receptor PhuR precursor; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene).
  
  
0.669
Your Current Organism:
Pseudomonas aeruginosa
NCBI taxonomy Id: 208964
Other names: P. aeruginosa PAO1, Pseudomonas aeruginosa PAO1, Pseudomonas sp. PAO1
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